In 1933, cancer researchers recognized the need to share knowledge and expertise globally and so founded the International Union Against Cancer (UICC). Since then, UICC has grown to embrace organizations engaged in all aspects of cancer prevention and control: voluntary cancer societies, research and treatment centres, public health authorities, patient support networks andadvocacy groups, and ministries of health. 

UICC is governed by its member organizations, which meet in a general assembly, held in conjunction with the World Cancer Congress, every two years. A board of 17 directors, elected by the general assembly, acts as the executive body of UICC.

UICC works closely with the World Health Organization (WHO), the International Agency for Research on Cancer (IARC), and the Programme of Action for Cancer Therapy (PACT), and has consultative status with the UN Economic and Social Council. It offers corporate partners a unique opportunity to demonstrate social responsibility on a global scale. Every two years, UICC brings together key stakeholders in a World Cancer Summit.